Discover some helpful tips to help you self-administer ENSPRYNG
You or your caregiver will have to be trained and approved by your healthcare provider before injecting ENSPRYNG. Once you or your caregiver have your healthcare provider's permission, along with the Instructions for Use, you can use the overview guide below.
The idea of self-injecting can be intimidating at first. If you’re new to it, or just want a refresher, we’ll walk you through an overview of the process. This information does not take the place of talking to your healthcare provider about your medical condition or treatment. Talk to your healthcare provider if you have any questions.
Step 1
Take the box containing your ENSPRYNG syringe out of the refrigerator, where it was stored at 36°F to 47°F (2°C to 8°C).
Always check that you have the right medicine and dose that your healthcare provider prescribed.
Check the expiration date on the back of the box and the seal on the front of the box. If the date has passed or the seal is broken, do not use.
Dispose of the syringe per the Instructions for Use and contact your healthcare provider.
Step 2
Open the box. Gently lift the syringe by the barrel and pull it out.
Check the expiration date on the syringe. The liquid should be clear and colorless to pale yellow. Some small bubbles are normal.
If the syringe is damaged or expired, or the liquid is cloudy, discolored, or has particles in it, do not use.
Step 3
Place the syringe on a clean, flat surface, set a timer for 30 minutes and let it come to room temperature. Keep it away from heating sources; do not warm up the syringe in direct sunlight, in a microwave, or with hot water. Do not remove the needle cover while the syringe is reaching room temperature.
Step 4
While you wait, you can gather the supplies you need for the injection: 1 alcohol pad, 1 sterile cotton ball or gauze, 1 small bandage, and 1 FDA-cleared or puncture-resistant sharps container for safe disposal of the needle cap and used syringe.
Step 5
First, wash your hands with soap and water.
Next, choose an injection site on your body: the front or middle of your thighs, or the lower part of your stomach.
Do not inject into moles, scars, bruises or areas where the skin is tender, red, hard or broken. The site should not be within 2 inches of your belly button.
Where you inject must be at least 1 inch away from where you last injected.
Wipe the injection site with an alcohol pad. Let it air dry, and do not touch it, or fan or blow on the area.
If you need help with the injection, ask your trained caregiver to assist you.
Step 6
Do not take the needle cap off until you are ready to inject ENSPRYNG.
When ready, take the cap off the needle and immediately dispose of it in an FDA-approved sharps disposal container. Do not put the needle cap back on after it has been removed as this may damage the needle.
Hold the barrel of the syringe using your thumb and index finger.
Use the syringe within 5 minutes, or the needle may clog. Do not touch the needle or let it touch any surfaces. Keep it away from children.
To check for air bubbles, hold the syringe with the needle pointing up. If there are any air bubbles, gently tap the syringe with your finger until the bubbles rise to the top. Slowly push the plunger rod just until all air is expelled from the syringe and needle, and a drop of drug solution is seen at the needle tip
Step 7
Hold the barrel of the syringe using your thumb and index finger. Do not insert the needle through clothing. With your other hand, pinch the area of the skin you have cleaned. Use a quick, dart-like motion to insert the needle at an angle between 45 to 90 degrees. Do it just once. Do not change the angle of the injection.
Step 8
Let go of the pinched skin. Then slowly inject the medicine by gently pushing the plunger all the way down. Gently release the plunger and allow the needle to come out of the skin at the same angle it was inserted. The needle shield should now cover the needle. If not, take extra care when disposing.
Step 9
Check the injection site. A small amount of blood or a drop of medicine may appear. You can press a cotton ball or gauze on it, but do not rub it. If needed, you can cover it with a small bandage. If the medicine comes in contact with your skin, wash with water.
That’s it. You did it. Now all you have to do is clean up.
Step 10
Immediately place the used ENSPRYNG syringe in an FDA-approved sharps disposal container, per the Instructions for Use.
If an FDA-cleared container isn't available, use a household container that is:
- Heavy-duty plastic and leak-resistant
- Upright and stable during use
- Securely sealed with a tight, puncture-resistant lid
- Clearly labeled as hazardous waste
Over time the container will fill up, so make sure you dispose of the container as instructed by your healthcare provider pharmacist, or community guidelines.
Never recycle your container, and only place it in household trash if explicitly allowed by local rules. Visit fda.gov/safesharpsdisposal for state-specific regulations and safety information
If you have any questions about self-injecting with ENSPRYNG, call: 844-677-7964. If you have any issues with your medication, please talk with your healthcare provider.
Tips for staying on track with treatment
Keep an injection diary
It's important to keep up with your ENSPRYNG injections. Writing down the date and site (eg, left abdomen or right thigh) of each dose can help, since you'll need to rotate injection sites. You can also make note of any reactions to discuss with your doctor.
Add monthly reminders
When you reach the maintenance phase of your dosing schedule, having 4 weeks between each dose of ENSPRYNG gives you a lot of time to get distracted by life. Adding reminders on your phone and/or calendar about your upcoming injection days can make it easier to plan ahead for them.
We want to support your journey
Explore our Pocket Injection Guide for helpful information about ENSPRYNG.