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We’re here to help with resources and support

We offer a range of services including financial assistance, community support, and more

Find the answers and support you're looking for with ENSPRYNG Access Solutions

We offer a number of support services, including:

  • Patient Navigator, your personal guide throughout your treatment with ENSPRYNG
  • Helping you get set up with ENSPRYNG supplemental injection training
  • Financial assistance to help with the cost of your ENSPRYNG

To learn more about support with ENSPRYNG visit ENSPRYNG Access Solutions or call 1-844-NSPRYNG

Personalized support throughout your ENSPRYNG treatment

Patient Navigators

Once you’ve been prescribed ENSPRYNG, as part of ENSPRYNG Access Solutions® you’ll be teamed up with a Patient Navigator who will be there to answer your questions and support you every step of the way.

Your Patient Navigator:

  • Works with your doctor’s office and/or specialty pharmacy to help you get your medicine
  • Explains how your insurance can cover your ENSPRYNG treatment
  • Helps you find financial assistance options, enroll in, and navigate the ENSPRYNG Co-pay Program, if you are eligible
  • Is available to answer questions about ENSPRYNG
  • Can teach you about ENSPRYNG Clinical Injection Training support

Personalized injection training

injection training

ENSPRYNG Clinical Education Managers provide supplemental injection training to patients or caregivers to ensure they are prepared to administer ENSPRYNG. Clinical Education Managers do not inject patients with ENSPRYNG.

  • They can set up a free 1:1 in-person or virtual injection training visit
  • They will provide ongoing injection training support throughout your ENSPRYNG treatment journey


Help with the cost of treatment with ENSPRYNG

Genentech is committed to helping you get the ENSPRYNG your doctor prescribed. Your Patient Navigator can help you find assistance options so you can pay for ENSPRYNG:

  • If you have a commercial insurance plan,* you may be able to use the ENSPRYNG Co-pay Program
  • If you have a commercial or public insurance plan (such as Medicare or Medicaid), you may be referred to an independent co-pay assistance foundation
  • If you have no insurance coverage or you can't pay for your medicine, the Genentech Patient Foundation§ may be able to help

*Commercial insurance includes plans you get through your employer or through a Health Insurance Marketplace like
Eligibility criteria apply. Not valid for patients using federal or state government programs to pay for their medications and or administration of their Genentech medication. Patient must be taking the Genentech medication for an FDA-approved indication. See full Terms and Conditions at
Independent co-pay assistance foundations have their own rules for eligibility. We cannot guarantee a foundation will help you. We can only refer you to a foundation that supports your disease state. We do not endorse or show financial preference for any particular foundation. The foundations we refer you to are not the only ones that might be able to help you.
§If you have health insurance, you should try to get other types of financial assistance, if available. You also need to meet income requirements. If you do not have insurance, or if your insurance does not cover your Genentech medicine, you must meet a different set of income requirements.

 ENSPRYNG patient Donna said "I realized how invaluable the support of others is when facing a disease like NMOSD."

Online and downloadable resources

Injection training with ENSPRYNG

Check out the Injection Training Video to see what taking ENSPRYNG is like or to refresh the training you got from your healthcare provider.

ENSPRYNG Administration Pocket Guide

This handy guide offers clear direction on how to administer ENSPRYNG.

Events about NMOSD

If you or someone you care about has neuromyelitis optica spectrum disorder (NMOSD), we invite you to a free educational event where you'll:

  • Learn more about treating NMOSD in adults who are AQP4-IgG(+) from an expert
  • Discover why ENSPRYNG may be the right choice for NMOSD
  • Hear an inspiring story from a person living with NMOSD

To register, call 855-367-7796.

Explore the NMOSD community

There are several websites for people just like you who are living with NMOSD. These sites are sponsored by various advocacy organizations, which are dedicated to providing support and resources, specifically to people with NMOSD. They include:

Selecting any of these links will take you to a site that is not owned or controlled by Genentech, Inc. Genentech, Inc. makes no representation as to the accuracy of the information contained on sites we do not own or control. Genentech does not recommend and does not endorse the content on any third-party websites. Your use of third-party websites is at your own risk and subject to the terms and conditions of use for such sites.

Find support online or through local support groups and events


Find tips for how to discuss NMOSD and your treatment options with your doctor.

 ENSPRYNG patient Peggy, diagnosed with NMOSD in 2014


ENSPRYNG is a prescription medicine used to treat neuromyelitis optica spectrum disorder (NMOSD) in adults who are aquaporin-4 (AQP4) antibody positive. It is not known if ENSPRYNG is safe and effective in children.

Who should not receive ENSPRYNG?

Do not take ENSPRYNG if you:

  • are allergic to ENSPRYNG or any of the ingredients in ENSPRYNG.
  • have an active hepatitis B infection.
  • have active or untreated inactive (latent) tuberculosis.

What is the most important information I should know about ENSPRYNG?

ENSPRYNG may cause serious side effects including:

  • Infections. ENSPRYNG can increase your risk of serious infections some of which can be life-threatening. Talk to your healthcare provider if you are being treated for an infection or call them right away if you think you have signs of an infection, with or without a fever, such as:
    • chills, feeling tired, muscle aches, cough that will not go away or a sore throat
    • skin redness, swelling, tenderness, pain or sores on your body
    • diarrhea, belly pain, or feeling sick
    • burning when you urinate or urinating more often than usual

Your healthcare provider will check if you have an infection and treat it if needed before you start or continue to take ENSPRYNG.

  • Your healthcare provider should test you for hepatitis and tuberculosis (TB) before you start taking ENSPRYNG.
  • All required vaccinations should be completed before starting ENSPRYNG. People using ENSPRYNG should not be given ‘live’ or ‘live-attenuated’ vaccines. ‘Live’ or ‘live-attenuated’ vaccines should be given at least 4 weeks before you start ENSPRYNG. Your healthcare provider may recommend that you get a ‘non-live’ (inactivated) vaccine, such as some of the seasonal flu vaccines. If you plan to get a ‘non-live’ (inactivated) vaccine it should be given, whenever possible, at least 2 weeks before you start ENSPRYNG.
  • Increased liver enzymes.
    Your healthcare provider should order blood tests to check your liver enzymes before and while you are taking ENSPRYNG. Your healthcare provider will tell you how often you will need to have these blood tests. Make sure you get all of your follow-up blood tests as ordered by your healthcare provider. Your healthcare provider will tell you if you need to wait to start ENSPRYNG if your liver enzymes are increased.
  • Low neutrophil count.
    ENSPRYNG can cause a decrease in your neutrophil counts in your blood. Neutrophils are white blood cells that help the body fight off bacterial infections. Your healthcare provider should order blood tests to check your neutrophil count while you are taking ENSPRYNG.
  • Serious allergic reactions.
    Serious allergic reactions that may be life-threatening have happened with other medicines like ENSPRYNG. Tell your healthcare provider before taking your next dose if you had hives, rash, or flushing after your injection. Seek medical attention right away if you have any symptoms of a serious allergic reaction, such as:
    • shortness of breath or trouble breathing
    • dizziness or feeling faint
    • swelling of your lips, face, or tongue
    • moderate or severe stomach (abdominal) pain or vomiting
    • chest pain

Before you take ENSPRYNG, tell your healthcare provider about all of your medical conditions, including if you:

  • have or think you have an infection. See "What is the most important information I should know about ENSPRYNG?"
  • have liver problems.
  • have ever had hepatitis B or are a carrier of the hepatitis B virus.
  • have had or have been in contact with someone with tuberculosis.
  • have had a recent vaccination or are scheduled to receive any vaccination.
  • are pregnant, think that you might be pregnant, or plan to become pregnant. It is not known if ENSPRYNG will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if ENSPRYNG passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you take ENSPRYNG.

Tell your healthcare provider about all the medicines you are taking, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the most common side effects of ENSPRYNG?
The most common side effects of ENSPRYNG include:

  • sore throat, runny nose (nasopharyngitis)
  • rash
  • fatigue
  • extremity pain
  • headache
  • upper respiratory tract infection
  • nausea
  • inflammation of the stomach lining (gastritis)
  • joint pain (arthralgia)

These are not all the possible side effects of ENSPRYNG.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Genentech at 1-888-835-2555.

For more information, call 1-844-NSPRYNG.

For additional safety information, please see the full Prescribing Information and Medication Guide.